La Roche-Posay Anthelios UVMune 400 Invisible Fluid Non-Perfumed SPF50+ 50ml

Meet the facial sunscreen that dermatologists recommend above all others. La Roche-Posay Anthelios UVMune 400 Invisible Fluid SPF50+ delivers groundbreaking broad-spectrum protection in a featherlight, invisible formula — so you’ll actually want to wear it every single day. Because glowing, protected skin starts with the right SPF.

Why Women Love This La Roche-Posay SPF50+ at Oh So Luxe

This isn’t just another sunscreen. Anthelios UVMune 400 is powered by MEXORYL 400 — La Roche-Posay’s exclusive patented filter and the first of its kind to specifically target ultra-long UVA rays (380–400nm). These are the deepest-penetrating rays responsible for photo-ageing, pigmentation and long-term skin damage — and most sunscreens simply don’t address them.

Combined with Mexoplex technology and Netlock Technology, the formula creates a homogeneous, invisible protective film that feels like a lightweight serum on skin. No greasiness. No white cast. No pilling under makeup. Just effortless, all-day protection that lets your natural radiance shine through.

La Roche-Posay is the No. 1 dermatologist-recommended sun protection brand in the UK — and this is their most celebrated formula.

Key Ingredients & Benefits

✧ MEXORYL 400 — exclusive filter targeting ultra-long UVA rays (380–400nm) for protection that exceeds EU standards

✧ Mexoplex Technology — advanced UV filter system delivering very high, broad-spectrum SPF50+ protection

✧ Netlock Technology — creates an invisible, homogeneous film for a serum-like, non-greasy finish

✧ La Roche-Posay Thermal Spring Water — soothing, antioxidant-rich water that calms and strengthens sensitive skin

✧ Glycerin — draws moisture into the skin for comfortable, hydrated wear all day

✧ Tocopherol (Vitamin E) — antioxidant support to help neutralise free radical damage from UV exposure

✧ Fragrance-Free & Hypoallergenic — ophthalmologically tested, suitable for contact lens wearers and reactive skin

✧ Ultra-Resistant Formula — highly resistant to water, sweat and sand; doesn’t migrate into eyes

How to Use La Roche-Posay Anthelios UVMune 400 for Best Results

✧ Shake well before each use

✧ Apply generously — approximately ½ teaspoon — to face and neck 15–20 minutes before sun exposure

✧ Use as the final step in your morning skincare routine, before makeup

✧ Reapply every 2 hours and after swimming, sweating or towel drying

✧ For maximum glow, layer over a vitamin C or hyaluronic acid serum in the morning

✧ Use daily year-round — UV damage happens even on cloudy UK days

Application & Care Tips

✧ Don’t skimp — most people apply only 25–50% of the recommended amount, which significantly reduces protection. Be generous.

✧ Pair with antioxidants — vitamin C serum underneath boosts your defence against free radical damage and enhances radiance

✧ Oily or combination skin? — consider the Oil Control version of Anthelios UVMune 400 for a mattifying finish

✧ Sensitive skin? — patch test first if you have extreme sensitivities; the fragrance-free formula is designed to minimise reaction risk

✧ Store correctly — keep out of direct sunlight and extreme heat to preserve the integrity of the UV filters

✧ This is the classic non-perfumed Invisible Fluid — also available in a Tinted version and an Oil Control variant

Frequently Asked Questions

Is La Roche-Posay Anthelios UVMune 400 suitable for sensitive skin?

Yes. The formula is fragrance-free, hypoallergenic and ophthalmologically tested — making it suitable for sensitive, reactive skin types, contact lens wearers, and even those undergoing dermatological treatment. It’s one of the most widely recommended SPFs by dermatologists in the UK.

Will it leave a white cast?

No. Thanks to Netlock Technology and the invisible fluid formula, it absorbs quickly and leaves no white cast on most skin tones. It also doesn’t pill under makeup, making it ideal for daily wear.

What makes MEXORYL 400 different from other UV filters?

MEXORYL 400 is La Roche-Posay’s exclusive patented filter — the first to specifically target ultra-long UVA rays (380–400nm). These rays penetrate deepest into the skin and are linked to photo-ageing and pigmentation. Most sunscreens don’t protect against them. This one does.

Can I wear it under makeup?

Absolutely. The lightweight, non-greasy texture absorbs like a serum and creates a smooth base for foundation, tinted moisturiser or BB cream. No pilling, no sliding — just a flawless, protected canvas.

How often should I reapply?

Reapply every 2 hours during sun exposure, and immediately after swimming, sweating or towel drying. For everyday office or indoor use, a morning application is typically sufficient — but reapplication is always recommended if you’re spending time outdoors.

Ready to Glow? ✨

Your skin deserves the best protection science can offer — in a formula that actually feels like a treat to wear. La Roche-Posay Anthelios UVMune 400 Invisible Fluid SPF50+ is the daily SPF that dermatologists trust, beauty editors rave about, and your future self will thank you for.

We offer free standard UK delivery on all orders over £50.

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